Volume 30, Issue 2, 2021


DOI: 10.24205/03276716.2020.4025

Study on the relationship between metabolic syndrome complications with non-alcoholic fatty liver and cardio-cerebrovascular diseases in people over 40 years old


Abstract
Introduction Metabolic syndrome (MS) is a cluster of numerous metabolically correlated risk factors that induce cardiovascular complications and other health problems. Objective The current study aims to evaluate the relationship between metabolic syndrome complicated with non-alcoholic fatty liver disease (NAFLD) and cardio-cerebrovascular diseases (CCD). Methods We analyze the incidence of cardio-cerebrovascular diseases in MS people over the age of 40 who had undergone physical examination. The attaining physicians initially assessed the patient for coronary heart disease or cerebrovascular disease. Furthermore, we measure various physical and biochemical parameters and blood indexes. Results Our result found that whether in the MS group or the non-MS group, the prevalence of cardio-cerebrovascular diseases in the NAFLD group (20.33% in the MS group and 7.20% in the non-MS group) was greater than that in the non-NAFLD group (7.65% in the MS group and 5.11% in the non-MS group). The risk of cardio-cerebrovascular diseases in the NAFLD group was 2.863 times that of the non-NAFLD group. However, it was not an independent risk factor in the non-MS group. Conclusions To sum up, NAFLD has an essential impact on the incidence of CCD. Therefore, NAFLD must be included as a crucial risk factor for CCD.

Keywords
Metabolic syndrome, cardio-cerebrovascular diseases, non-alcoholic fatty liver disease

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