Volume 17, Issue 3
DOI: 10.53555/03276716.2008.02
Lipid Profile in Diabetic Patients Attending A Tertiary Care Hospital In Western Uttar Pradesh
Abstract
Background: Dyslipidemia is a prevalent condition frequently observed in diabetic individuals, leading to cardiovascular complications. Objective: To identify lipid irregularities in patients with diabetes. Methods: This research was performed at the department of Medicine, Santosh Medical College, Ghaziabad, Uttar Pradesh over the duration from January 2008 to Aug 2008. We analyzed the lipid profiles and fasting blood sugar levels of 100 type-1 diabetic patients, 100 type-2 diabetic patients, and 50 healthy controls after obtaining informed consent. Serum samples were evaluated for fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL) utilizing standard biochemical techniques. Data were gathered using a pre-designed, pre-tested proforma and assessed with SPSS 17.0 (Trial version). Results: The highest number of individuals (37% and 44%) were within the age range of 20-29 years for type-1 DM and 50-59 years for type-2 DM, respectively. 53% of type-1 DM cases and 70% of type-2 DM cases exhibited fasting blood sugar levels below 140 mg/dl. Conversely, 49% of type1 DM patients and 30% of type-2 DM patients reported postprandial blood sugar levels exceeding 200 mg/dl. A significant majority of type-2 DM patients (72%) had elevated serum cholesterol levels, while only 12% of type-1 DM patients demonstrated high cholesterol levels. Moreover, 95% of type-1 DM patients maintained normal serum triglyceride levels (10-190 mg/dl), in contrast to only 26% of type-2 DM subjects. Serum LDL levels were elevated (>160 mg/dl) in 78% of type-2 DM patients, while only 19% of type-1 DM patients exhibited higher values. All type-2 DM patients presented with normal serum HDL levels.Conclusions: The prevalence of elevated cholesterol, triglycerides, and LDL levels was significantly greater in the diabetic population, highlighting their higher susceptibility to dyslipidemia, which may contribute to cardiovascular disorders.
Keywords
Dyslipidemia, Diabetes, Serum cholesterol, Serum triglyceride, Lipid profile, Serum LDL